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2014 Grant Awarded

Auburn’s Dr. Jennifer Koziol awarded grant for Tritichomonas research

The Theriogenology Foundation has committed $4,850.00 in funding toward the investigation of “In vitro efficacy of anti-protozoal compounds against Tritrichomonas foetus”.
The study was designed by researchers at Auburn University College of Veterinary Medicine led by Dr. Jennifer Koziol. Dr. Koziol said, “Our group has proposed that an anti-protozoal compound can be formulated to be applied to the prepuce and penis of the bull to cure those infected with Tritrichomonas foetus. A preliminary in vitro study by our group has already shown promising results. Topical and oral formulations are not novel and have been used in the past to treat infected bulls, but these drugs are no longer manufactured or have been banned by the FDA respectively.”
“The successful formulation of an anti-protozoal compound to treat bulls infected with Tritrichomonas foetus could have major impacts on the bovine industry as a whole, as millions of dollars are lost every year due to this venereal disease,” Dr. Koziol said. 

 


2013 Grants Awarded

Dr. Chance Armstrong awarded research grant 

The Theriogenology Foundation has generously funded a research project to utilize a polymerase chain reaction to test bovine semen and pre-seminal fluid for the presence of Tritrichomonas foetus, a venereally transmitted parasite the results in the loss of millions of dollars annually to the cattle industry. The project is led by Dr. Chance Armstrong with input from clinicians and basic scientists from the Bovine Venereal Disease working group at the Auburn University College of Veterinary Medicine. If infected bulls can be accurately identified with this methodology, testing could be simplified, perhaps utilizing samples collected by practitioners during a routine breeding soundness examination. A small pilot study yielded encouraging results and the $5,000 provided by the Theriogenology Foundation will allow investigation of this novel diagnostic approach. 


Dr. Maria Schnobrich awarded research grant for equine pregnancy loss

The Theriogenology Foundation has committed $3,840.00 in funding toward an investigation into the relationship between early embryonic loss and serum Amyloid A in mares.
The study was designed by a combined research group from Rood and Riddle Equine Hospital and The Gluck Institute at the University of Kentucky led by Dr. Maria Schnobrich. Dr. Schnobrich (UPENN ‘08) described the work “We are interested in investigating the relationship between Serum Amyloid A blood levels at the time of ovulation and early pregnancy diagnosis (approximately 16 days post-ovulation) and determining if there is a consistent relationship between these levels and mares that subsequently experience pregnancy loss prior to 60 days. Previous research has suggested that higher levels of serum Amyloid A at the time of ovulation is associated with increased pregnancy loss in early gestation and we wanted to test this in a field setting.”
Her group conducted a large prospective study evaluating over 1,000 Thoroughbred mares in a private practice setting during the 2014 breeding season in Central Kentucky. Serum Amyloid A levels at the time of ovulation and at first pregnancy diagnosis were not associated with increased pregnancy loss. This study has helped understand the clinical applications of Serum Amyloid A levels in the mare, and demonstrated it is a poor predictor of early pregnancy loss.
The results of this study were presented at the annual 2014 Society for Theriogenology meeting in Portland, OR and are currently being prepared for publication.

 


2012 Grant Awarded

Tritrichomonas foetus study planned

The Theriogenology Foundation has committed $5,403.20 in funding toward an investigation into the chronic nature of infection with Tritrichomonas foetus in naturally infected bulls.

The study was designed by a research group at the Auburn University College of Veterinary Medicine led by Dr. Andrew Lovelady. Dr. Lovelady (AUB ‘04) said, "Our group has proposed the theory that the accessory sex organs of the bull may play a role in the organism’s ability to establish a chronic infection within some bulls. Although this theory has been briefly investigated in the past, we believe that we have newer technologies and sufficient evidence available at present to reinvestigate this theory.”

His group conducted a small pilot study which, he said, has yielded evidence supporting its theory.

"Validation of our theory through this project could reveal important information regarding the epidemiology/pathophysiology of this economically devastating parasite,” Dr. Lovelady said.

The American Association of Bovine Practitioners has awarded an AABP Research Assistantship to Dr. Lovelady, and the initial 75 percent of the $5,000 grant was released at the opening ceremony of the AABP annual conference Sept. 20 in Montreal.

Link to AVMA article
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